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R&D reagents

Product > R&D reagents
Buspirone HCl, 99% (HPLC)
CAS No J10144-100mg
제품번호 AK Sci.(USA)
제조사 수입산
재고 1 EA
금액 177,000원



N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride



 

※ 화학명 : Buspirone HCl, 99% (HPLC)

 

※ 등급 : APIs and Bioactives > Serotonin Agonists

※ 판매 포장단위 : 100mg

 

※ 화학식 : C21H32ClN5O2

 

※ CAS # : [33386-08-2]

 


 

IDENTITY
CAS Registry #: [33386-08-2]
MDL Number: MFCD00078569
MF: C21H32ClN5O2
MW: 421.96
EINECS: 251-489-4
SPECIFICATIONS & PROPERTIES
Purity: 99% (HPLC)
Available Spectra:

 

LCMS, HPLC

Physical Form: White to off-white powder
Melting Point: 201-206°C
Long-Term Storage:

 

Store long-term at 2-8°C

Shipping: Regulated for Shipping
UN #: 2811
Hazard Class: 6.1
Packing Group: III

BIOLOGICAL INFO
Application(s): Serotonin receptor agonist
Form: HCl salt

REVIEW
Buspirone binds to 5-HT type 1A serotonin receptors on presynaptic neurons in the dorsal raphe and on postsynaptic neurons in the hippocampus, thus inhibiting the firing rate of 5-HT-containing neurons in the dorsal raphe. Buspirone also binds at dopamine type 2 (DA2) receptors, blocking presynaptic dopamine receptors. Buspirone increases firing in the locus ceruleus, an area of brain where norepinephrine cell bodies are found in high concentration. The net result of buspirone actions is that serotonergic activity is suppressed while noradrenergic and dopaminergic cell firing is enhanced.

Risk Description(s)
R25: Toxic if swallowed.

Safety Description(s)
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).