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R&D reagents

Product > R&D reagents
Guanfacine HCl, 98%
CAS No 69635-10mg
제품번호 AK Sci.(USA)
제조사 수입산
재고 1 EA
금액 72,000원
포장단위



N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride
N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride





※ 화학명 : Guanfacine HCl, 98%

 

※ 등급 : APIs and Bioactives > Adrenergic Agonists

 

※ 판매 포장단위 : 10mg , 50mg

 

※ 화학식 : C9H10Cl3N3O

 

※ CAS # : [29110-48-3]

 

 

IDENTITY
CAS Registry #: [29110-48-3]
MDL Number: MFCD00798230
MF: C9H10Cl3N3O
MW: 282.55
SPECIFICATIONS & PROPERTIES
Purity: 98%
Physical Form: White needles
Melting Point: 213-219°C
Long-Term Storage:

 

Store at room temperature

Shipping: Not Regulated for Shipping

BIOLOGICAL INFO
Solubility: H2O: soluble 12mg/mL at 60 °C
Application(s): Antihypertensive agent, a-2 noradrenergic receptor agonist
Form: HCl salt

REVIEW
Guanfacine selectively stimulates central alpha(2)-adrenergic receptors, resulting in inhibition of sympathetic vasomotor centers, which contributes predominantly to the hypotensive effects of the drug. Central effects of guanfacine lead to reduced peripheral sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This results in a decrease in peripheral vascular resistance and a reduction in heart rate. The stimulation of peripheral alpha(2)-adrenergic receptors may also contribute to hypotensive effects.

Risk Description(s)
R36/37/38: Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25: Avoid contact with skin and eyes.