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R&D reagents

Product > R&D reagents
Levalbuterol HCl, 98% (HPLC)
CAS No S105-10mg
제품번호 AK Sci.(USA)
제조사 수입산
재고 1 EA
금액 129,000원
포장단위



(R)-salbutamol hydrochloride
Levosalbutamol hydrochloride



 

※ 화학명 : Levalbuterol HCl, 98% (HPLC)

 

※ 등급 : APIs and Bioactives > Adrenergic Agonists

 

※ 판매 포장단위 : 10mg , 50mg

 

※ 화학식 : C13H22ClNO3

 

※ CAS # : [50293-90-8]


 

IDENTITY
CAS Registry #:

 

[50293-90-8]

MDL Number: MFCD08067728
MF: C13H22ClNO3
MW: 275.77
SPECIFICATIONS & PROPERTIES
Purity: 98% (HPLC)
Available Spectra: LCMS, HPLC, Polarimetry
Physical Form: White to tan crystalline powder
Melting Point: 188-195°C
Optical Rotation: -25.0° - -35.0° (c=0.1, H2O)
Long-Term Storage:

 

Store long-term at 2-8°C

Shipping: Not Regulated for Shipping

BIOLOGICAL INFO
Solubility: H2O: =15 mg/mL
Application(s): beta2-Adrenergic receptor agonist
Form: HCl salt

REVIEW
Activation of beta2-adrenergic receptors on airway smooth muscle leads to the activation of adenylcyclase and to an increase in the intracellular concentration of cyclic-3\, 5\-adenosine monophosphate (cyclic AMP). This increase in cyclic AMP leads to the activation of protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular ionic calcium concentrations, resulting in relaxation. Levalbuterol relaxes the smooth muscles of all airways, from the trachea to the terminal bronchioles. Levalbuterol acts as a functional antagonist to relax the airway irrespective of the spasmogen involved, thus protecting against all bronchoconstrictor challenges. Increased cyclic AMP concentrations are also associated with the inhibition of release of mediators from mast cells in the airway.

Risk Description(s)
R22: Harmful if swallowed.
R37/38: Irritating to respiratory system and skin
R41: Risk of serious damage to the eyes.

Safety Description(s)
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39: Wear eye/face protection.