

| alpha-(Aminomethyl)-4-hydroxybenzyl alcohol hydrochloride |
| (+/-)-1-(4-Hydroxyphenyl)-2-aminoethanol hydrochloride |
¡Ø ÈÇиí : Octopamine HCl, 98%
¡Ø µî±Þ : APIs and Bioactives > Adrenergic Agonists
¡Ø ÆÇ¸Å Æ÷Àå´ÜÀ§ : 1g , 5g , 10g , 25g
¡Ø ÈÇÐ½Ä : C8H12ClNO2
¡Ø CAS # : [770-05-8]
|
| IDENTITY |
|
| CAS Registry #: |
[770-05-8] |
| MDL Number: |
MFCD00012881 |
| MF: |
C8H12ClNO2 |
| MW: |
189.64 | |
| SPECIFICATIONS & PROPERTIES |
|
| Purity: |
98% |
| Physical Form: |
Crystals |
| Melting Point: |
169-171¡ÆC |
| Long-Term Storage: |
Store at room temperature |
| Shipping: |
Not Regulated for Shipping | | |
BIOLOGICAL INFO |
|
| Form: |
HCl salt |
REVIEWOctopamine (beta, 4-dihydroxyphenethylamine) is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems. Octopamine HCl, a racemate, is an alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses.. Under the trade names Epirenor, Norden, and Norfen, octopamine is also used clinically as a sympathomimetic agent. It is also a neurotransmitter in some invertebrates.
REFERENCES
[1] |
Mannich, C.; Thiele, E. beta-Hydroxy-beta-phenylethylamine and related compounds. Archiv der Pharmazie (Weinheim, Germany) (1915), 253, 181-95. |
| [2] |
Corrigan, John R.; Langerman, Marie-Jo; Moore, Maurice L. N-Substituted 1-(p-hydroxyphenyl)-2-aminoethanols. Journal of the American Chemical Society (1945), 67, 1894-6. |
| [3] |
Fujiwara, Motohatsu; Hattori, Keisuke; Mizusawa, Hideo; Muryobayashi, Takashi; Kato, Yoshiko Pharmacological action octopamine, with special reference to biochemical conversion to noradrenaline. Japanese Journal of Pharmacology (1968), 18(1), 113-29. |
| [4] |
Jagiello-W?jtowicz E. Mechanism of central action of octopamine. Pol J Pharmacol Pharm. 1979 Sep-Oct;31(5):509-16. |
Risk Description(s)
| R36/37/38: |
Irritating to eyes, respiratory system and skin |
Safety Description(s)
| S24/25: |
Avoid contact with skin and eyes. |


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