PRODUCT

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R&D reagents

Product > R&D reagents
Octopamine HCl, 98%
CAS No M790-1g
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alpha-(Aminomethyl)-4-hydroxybenzyl alcohol hydrochloride
(+/-)-1-(4-Hydroxyphenyl)-2-amino­ethanol hydrochloride



 

¡Ø È­Çиí : Octopamine HCl, 98%

 

¡Ø µî±Þ : APIs and Bioactives > Adrenergic Agonists

 

¡Ø ÆÇ¸Å Æ÷Àå´ÜÀ§ : 1g , 5g , 10g , 25g

 

¡Ø È­ÇÐ½Ä : C8H12ClNO2

 

¡Ø CAS # : [770-05-8]

 

 

 

IDENTITY
CAS Registry #: [770-05-8]
MDL Number: MFCD00012881
MF: C8H12ClNO2
MW: 189.64
SPECIFICATIONS & PROPERTIES
Purity: 98%
Physical Form: Crystals
Melting Point: 169-171¡ÆC
Long-Term Storage:

 

Store at room temperature

Shipping: Not Regulated for Shipping

BIOLOGICAL INFO
Form: HCl salt

REVIEW

Octopamine (beta, 4-dihydroxyphenethylamine) is an endogenous biogenic amine that is closely related to norepinephrine, and has effects on the adrenergic and dopaminergic systems. Octopamine HCl, a racemate, is an alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses.. Under the trade names Epirenor, Norden, and Norfen, octopamine is also used clinically as a sympathomimetic agent. It is also a neurotransmitter in some invertebrates.

REFERENCES
[1] Mannich, C.; Thiele, E. beta-Hydroxy-beta-phenylethylamine and related compounds. Archiv der Pharmazie (Weinheim, Germany) (1915), 253, 181-95.
[2] Corrigan, John R.; Langerman, Marie-Jo; Moore, Maurice L. N-Substituted 1-(p-hydroxyphenyl)-2-aminoethanols. Journal of the American Chemical Society (1945), 67, 1894-6.
[3] Fujiwara, Motohatsu; Hattori, Keisuke; Mizusawa, Hideo; Muryobayashi, Takashi; Kato, Yoshiko Pharmacological action octopamine, with special reference to biochemical conversion to noradrenaline. Japanese Journal of Pharmacology (1968), 18(1), 113-29.
[4] Jagiello-W?jtowicz E. Mechanism of central action of octopamine. Pol J Pharmacol Pharm. 1979 Sep-Oct;31(5):509-16.

Risk Description(s)
R36/37/38: Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25: Avoid contact with skin and eyes.