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¡Ø ÈÇиí : Fenoldopam, 98% (HPLC)
¡Ø µî±Þ : APIs and Bioactives > Dopamine Agonists
¡Ø ÆÇ¸Å Æ÷Àå´ÜÀ§ : 10mg , 25mg
¡Ø ÈÇÐ½Ä : C16H16ClNO3
¡Ø CAS # : [67227-56-9]
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| IDENTITY |
|
| CAS Registry #: |
[67227-56-9] |
| MDL Number: |
MFCD00865806 |
| MF: |
C16H16ClNO3 |
| MW: |
305.76 | |
| SPECIFICATIONS & PROPERTIES |
|
| Purity: |
98% (HPLC) |
| Available Spectra: |
NMR, LCMS, HPLC |
| Physical Form: |
Yellow powder |
| Melting Point: |
210-214¡ÆC |
| Long-Term Storage: |
Store at room temperature |
| Shipping: |
Not Regulated for Shipping | | |
BIOLOGICAL INFO |
|
| Application(s): |
Dopamine agonist | REVIEW Fenoldopam is a rapid-acting vasodilator. It is an agonist for D1-like dopamine receptors and binds with moderate affinity to alpha-2-adrenoceptors. It has no significant affinity for D2-like receptors, alpha-1 and beta--adrenoceptors, 5HT1 and 5HT2 receptors, or muscarinic receptors. Fenoldopam is a racemic mixture with the R-isomer responsible for the biological activity. The R-isomer has approximately 250-fold higher affinity for D1-like receptors than does the S-isomer. In non-clinical studies, fenoldopam had no agonist effect on presynaptic D2-like dopamine receptors, or alpha- or beta- -adrenoceptors, nor did it affect angiotensin-converting enzyme activity. Fenoldopam may increase norepinephrine plasma concentration.
Risk Description(s)
| R22: |
Harmful if swallowed. |
| R36: |
Irritating to eyes. |
| R42/43: |
May cause sensitization by inhalation and skin contact | Safety Description(s)
| S22: |
Do not breathe dust . |
| S26: |
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| S36/37/39: |
Wear suitable protective clothing, gloves and eye/face protection. |
 |


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