

| 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride |
¡Ø ÈÇиí : Ropinirole HCl, 99% (HPLC)
¡Ø µî±Þ : APIs and Bioactives > AChR Agonists
¡Ø ÆÇ¸Å Æ÷Àå´ÜÀ§ : 25mg , 100mg , 1g
¡Ø ÈÇÐ½Ä : C16H25ClN2O
¡Ø CAS # : [91374-20-8]
|
| IDENTITY |
|
| CAS Registry #: |
[91374-20-8] |
| MDL Number: |
MFCD01754173 |
| MF: |
C16H25ClN2O |
| MW: |
296.84 | |
| SPECIFICATIONS & PROPERTIES |
|
| Purity: |
99% (HPLC) |
| Available Spectra: |
NMR, LCMS, HPLC |
| Physical Form: |
Light yellow powder |
| Melting Point: |
235-243¡ÆC |
| Long-Term Storage: |
Store at room temperature |
| Shipping: |
Not Regulated for Shipping | | |
BIOLOGICAL INFO |
|
| Solubility: |
H2O: >10 mg/mL |
| Application(s): |
Selective dopamine D2 receptors inhibitor |
| Form: |
HCl salt |
REVIEWRopinirole binds the dopamine receptors D3 and D2. Although the precise mechanism of action of ropinirole as a treatment for Parkinsons disease is unknown, it is believed to be related to its ability to stimulate these receptors in the striatum. This conclusion is supported by electrophysiologic studies in animals that have demonstrated that ropinirole influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra, the site of neurons that send projections to the striatum.
Risk Description(s)
| R22: |
Harmful if swallowed. |
| R50/53: |
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment |
Safety Description(s)
| S36: |
Wear suitable protective clothing. |
| S60: |
This material and its container must be disposed of as hazardous waste. |
| S61: |
Avoid release to the environment. Refer to special instructions/Safety data sheets. |



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